Premium grape seed extract products for your health

100% grapes. Nothing more.

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MegaNatural®: From Farm to Finish

MegaNatural® grape seed extracts are produced from an abundant supply of quality grapes, grown and processed sustainably in the heart of America’s wine country. Polyphenolics manages every step of the process, from the initial wine grape and seed selection to the final extraction of the finished material. Polyphenolics is a division of Division of California Natural Color / E.&J. Gallo Winery Inc., the world’s largest premium wine company. Just as our parent company strives for excellence in making premium wines, Polyphenolics strives for excellence in making premium grape seed extracts. Watch our video to learn more.

Clinically shown, patented and 100% pure grape seed extract

Polyphenolics’ MegaNatural® grape seed extracts contain 100% grapes. Nothing more. Our unique, condition-specific products have earned four U.S. patents and numerous additional patents around the world. Polyphenolics also invests heavily in original laboratory and clinical research. It’s the only way to confirm the efficacy of our extracts. Made using a patented hot water extraction process, MegaNatural® grape seed extracts are verified to be consistent in every batch, which means consistent results in your supplement.

Heart Health

MegaNatural®-BP is clinically shown to help maintain blood pressure levels within a healthy range.


MegaNatural®-Gold has been shown to have a greater antioxidant capacity than vitamins C and E or beta-carotene.

Sports Nutrition

MegaNatural®-BP helps support endothelial function by maintaining healthy nitric oxide levels that are within the normal range. This helps support healthy vasodilation and blood flow.

Grape Seed Extracts and their Role in Sports Nutrition

Download the latest whitepaper from Polyphenolics President Jim Kennedy on the role of MegaNatural® Grape Seed Extracts in sports nutrition.

Download the Whitepaper (PDF)

Where to find MegaNatural®

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